Nagoor Meeran MF, Sharma C, Goyal SN, Kumar S, Ojha S. CB2 receptor-selective agonists
as candidates for targeting infection, inflammation, and immunity in SARS-CoV-2 infections.
Drug Dev Res. 2020 Nov 15. doi: 10.1002/ddr.21752.
Patil AS, Mahajan UB, Agrawal YO, Patil KR, Patil CR, Ojha S, Sharma C, Goyal SN.
Plant-derived natural therapeutics targeting cannabinoid receptors in metabolic syndrome
and its complications: A review. Biomed Pharmacother. 2020 Oct 22;132:110889. doi: 10.1016/j.biopha.2020.110889.
Jayaraj RL, Beiram R, Azimullah S, Mf NM, Ojha S, Adem A, Jalal FY. Valeric Acid Protects
Dopaminergic Neurons by Suppressing Oxidative Stress, Neuroinflammation and Modulating
Autophagy Pathways. Int J Mol Sci. 2020 Oct 16;21(20):7670. doi: 10.3390/ijms21207670.
Javed H, Meeran MFN, Azimullah S, Bader Eddin L, Dwivedi VD, Jha NK, Ojha S. α-Bisabolol,
a Dietary Bioactive Phytochemical Attenuates Dopaminergic Neurodegeneration through
Modulation of Oxidative Stress, Neuroinflammation and Apoptosis in Rotenone-Induced
Rat Model of Parkinson's disease. Biomolecules. 2020 Oct 8;10(10):1421. doi: 10.3390/biom10101421.
El Nebrisi E, Javed H, Ojha S, Oz M, Shehab S. Neuroprotective Effect of Curcumin
on the Nigrostriatal Pathway in a 6-Hydroxydopmine-Induced Rat Model of Parkinson's
Disease is Mediated by α7-Nicotinic Receptors. Int J Mol Sci. 2020 Oct 3;21(19):7329.
doi: 10.3390/ijms21197329.
Hashiesh HM, Meeran MFN, Sharma C, Sadek B, Kaabi JA, Ojha S. Therapeutic Potential
of β-Caryophyllene: A Dietary Cannabinoid in Diabetes and Associated Complications.
Nutrients. 2020 Sep 28;12(10):2963. doi: 10.3390/nu12102963.
Birari L, Wagh S, Patil KR, Mahajan UB, Unger B, Belemkar S, Goyal SN, Ojha S, Patil
CR. Aloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative
stress and pro-inflammatory cytokines. Cancer Chemother Pharmacol. 2020 Sep;86(3):419-426.
doi: 10.1007/s00280-020-04125-w.
Agrawal YO, Mahajan UB, Mahajan HS, Ojha S. Methotrexate-Loaded Nanostructured Lipid
Carrier Gel Alleviates Imiquimod-Induced Psoriasis by Moderating Inflammation: Formulation,
Optimization, Characterization, In-Vitro and In-Vivo Studies. Int J Nanomedicine.
2020 Jul 7;15:4763-4778. doi: 10.2147/IJN.S247007.
Eissa N, Azimullah S, Jayaprakash P, Jayaraj RL, Reiner D, Ojha S, Beiram R, Stark
H, Łażewska D, Kieć-Kononowicz K, Sadek B. The Dual-Active Histamine H3Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like
Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice. Int J Mol
Sci. 2020 Jun 3;21(11):3996. doi: 10.3390/ijms21113996.
Alachkar A, Azimullah S, Lotfy M, Adeghate E, Ojha S, Beiram R, Łażewska D, Kieć-Kononowicz
K, Sadek B. Antagonism of Histamine H3 receptors Alleviates Pentylenetetrazole-Induced
Kindling and Associated Memory Deficits by Mitigating Oxidative Stress, Central Neurotransmitters,
and c-Fos Protein Expression in Rats. Molecules. 2020 Mar 30;25(7):1575. doi: 10.3390/molecules25071575.
Nauman J, Soteriades ES, Hashim MJ, Govender R, Al Darmaki RS, Al Falasi RJ, Ojha
S, Masood-Husain S, Javaid SF, Khan MA. Global Incidence and Mortality Trends due
to Adverse Effects of Medical Treatment, 1990-2017: A Systematic Analysis from the
Global Burden of Diseases, Injuries and Risk Factors Study. Cureus. 2020 Mar 14;12(3):e7265.
doi: 10.7759/cureus.7265.
Venkataraman B, Ojha S, Belur PD, Bhongade B, Raj V, Collin PD, Adrian TE, Subramanya
SB. Phytochemical drug candidates for the modulation of peroxisome proliferator-activated
receptor γ in inflammatory bowel diseases. Phytother Res. 2020 Jul;34(7):1530-1549.
doi: 10.1002/ptr.6625. Epub 2020 Feb 3.
Alachkar A, Ojha S, Sadeq A, Adem A, Frank A, Stark H, Sadek B. Experimental Models
for the Discovery of Novel Anticonvulsant Drugs: Focus on Pentylenetetrazole-Induced
Seizures and Associated Memory Deficits. Curr Pharm Des. 2020;26(15):1693-1711. doi: 10.2174/1381612826666200131105324.
Nagoor Meeran MF , Azimullah S , Laham F , Tariq S , Goyal SN , Adeghate E , Ojha
S . α-Bisabolol protects against β-adrenergic agonist-induced myocardial infarction
in rats by attenuating inflammation, lysosomal dysfunction, NLRP3 inflammasome activation
and modulating autophagic flux. Food Funct. 2020 Jan 29;11(1):965-976. doi: 10.1039/c9fo00530g.
Elarabi HF, Hasan N, Marsden J, Radwan D, Adem A, Almamari S, Elrasheed A. Therapeutic
Drug Monitoring in Buprenorphine/Naloxone Treatment for Opioid Use Disorder: Clinical
Feasibility and Optimizing Assay Precision. Pharmacopsychiatry. 2020 Apr;53(3):115-121.
Ismail L, Materwala H, Karduck AP, Adem A. Requirements of Health Data Management
Systems for Biomedical Care and Research: Scoping Review. J Med Internet Res. 2020
Jul 7;22(7):e17508. doi: 10.2196/17508.
Behl S, Adem A, Hussain A, Singh J. Effect of the anti-retroviral drug, rilpivirine,
on human subcutaneous adipose cells and its nutritional management using quercetin.
Mol Cell Biochem. 2020 Aug;471(1-2):1-13.
AlNeyadi SS, Amir N, Ghattas MA, Atatreh N, Alketbi SS, Ajeil RA, Adem A. Controlled
Release of Pyrimidine Compound Using Polymeric Coated ZIF-8 Metal-Organic Framework
as Glucagon-Like Peptide-1 Receptor Agonist Carrier. Molecules. 2020 Sep 20;25(18):E4313.
Islam AUS, Hellman B, Nyberg F, Amir N, Jayaraj RL, Petroianu G, Adem A. Myrcene Attenuates
Renal Inflammation and Oxidative Stress in the Adrenalectomized Rat Model. Molecules.
2020 Sep 30;25(19):E4492.
Mahmoud A. Ali , Hassan Abu Damir, Osman M. Ali, Naheed Amir, Saeed Tariq, Michael
P. Greenwood, Panjiao Lin, Benjamin Gillard, David Murphy and Abdu Adem. The effect
of long-term dehydration and subsequent rehydration on markers of inflammation, oxidative
stress and apoptosis in the camel kidney. BMC Veterinary Research, In press,2020.
doi.org/10.1186/s12917-020-02628-5.
Al-Dirbashi OY, Sharma C, Al Dahouri N, Al Aidaros A, Al-Muhairi S, Beiram R,Gariballa
S, Al Kaabi J. Role of Functional Biomarkers to Identify Early Vitamin B12 Deficiency
in Patients with Sleeve Gastrectomy: A Cross-Sectional Study. Medicina (Kaunas). 2020
Mar 20;56(3):142.
JayarajRL, Azimullah S, Beiram R*. Diabetes as a risk factor for Alzheimer's disease
in the Middle East and its shared pathological mediators. Saudi J Biol Sci. 2020 Feb;27(2):736-750.
Sadeq A, Alkhidir IY, Aburuz S, Mellal AA, Al Najjar MS, Elnour AA. Risk factors for
hospital readmission of patients with heart failure: A cohort study. Pharm Bioallied
Sci. 2020 12:335-343.
AbuRuz S, Jaber D, Basheti I, Sadeq A, Arafat M, AlAhmad M, Said A. Impact of pharmacist
interventions on drug-related problems in general surgery patients: a randomised controlled
trial European Journal of Hospital Pharmacy, 2020.
Aburuz S, Jaber D, AlAhmad M, Basheti I, Arafat M, Sadeq A, Said A. Drug-related problems
and the value of a pharmaceutical care service in general surgery patients. International
Journal of Clinical Pharmacy. 2020, 42: 817-817.
Arafat M, Fahelelbom KM, Sarfraz MK, Bostanudin MF, Sharif Q, Esmaeil A, AL Hanbali
OA, Aburuz S. Comparison between branded and generic furosemide 40 mg tablets using
thermal gravimetric analysis and Fourier transform infrared spectroscopy. Pharm Bioallied
Sci. 2020, 12: 489-498.
Stip E, Rizvi TA, Javaid S, Aburuz S, Ahmed NN, Abdel Aziz K, Arnone D, Subbarayan
A, Al Mugaddam F, and Khan G. The Large action of Chlorpromazine: Translational and
Transdisciplinary Considerations in the Face of COVID-19. Frontiers in Pharmacology
| doi: 10.3389/fphar.2020. 577678.
Kappes L, Amer RL, Sommerlatte S, Bashir G, Plattfaut C, Gieseler F, Gemoll T, Busch
H, Altahrawi A, Al-Sbiei A, Haneefa SM, Arafat K, Schimke LF, Khawanky NE, Schulze-Forster
K, Heidecke H, Kerstein-Staehle A, Marschner G, Pitann S, Ochs HD, Mueller A, Attoub
S, Fernandez-Cabezudo MJ, Riemekasten G, Al-Ramadi BK, Cabral-Marques O. Ambrisentan,
an endothelin receptor type A-selective antagonist, inhibits cancer cell migration,
invasion, and metastasis. Sci Rep. 2020 Sep 28; 10(1):15931. doi: 10.1038/s41598-020-72960-1.
Al-Sadik H, Sugathan S, Saseedharan P, Sulaiman S, Beegam S, Nemmar A, Attoub S, Karam
SM. Effects of Diesel Exhaust Particles on Mouse Gastric Stem Cells. Life (Basel).
2020 Aug 12; 10(8):E149. doi: 10.3390/life10080149.
Raj V, Venkataraman B, Almarzooqi S, Chandran S, Ojha SK, Attoub S, Adrian TE, Subramanya
SB. Nerolidol Mitigates Colonic Inflammation: An Experimental Study Using both In
Vivo and In Vitro Models. Nutrients. 2020; 12(7):E2032. doi: 10.3390/nu12072032.
Conlon JM, Attoub S, Musale V, Leprince J, Casewell NR, Sanz L, Calvete JJ. Isolation
and characterization of cytotoxic and insulin-releasing components from the venom
of the black-necked spitting cobra Naja nigricollis (Elapidae). Toxicon X. 2020; 6:100030.
doi: 10.1016/j.toxcx.2020.100030.
Eissa N, Jayaprakash P, Stark H, Łażewska D, Kieć-Kononowicz K, Sadek B. Simultaneous
Blockade of Histamine H3 Receptors and Inhibition of Acetylcholine Esterase Alleviate
Autistic-like Behaviors in BTBR T+ tf/J Mouse Model of Autism. Biomolecules 2020;
10(9), 1251.
Łażewska D, Bajda M, Kaleta M, Zaręba P, Doroz-Płonka A, Siwek A, Alachkar A, Mogilski
S, Saad Ali, Kuder K, Olejarz-Maciej A, Godyń J, Stary D, Więcek M, Sadek B, Malawska
B, Kononowicz KK. Rational design of new multitarget histamine H3 receptor ligands
as potential candidates for treatment of Alzheimer’s Disease. Eur J Med Chem. 2020;207.
Eissa N, Sadeq A, Sasse A, Sadek B. Role of neuroinflammation in autism spectrum disorder
and the emergence of brain histaminergic system. Lessons also for BPSD? Front. Pharmacol.
2020; 11:833.
(2019)
Adem A, Madjid N, Stiedl O, Bonito-Oliva A, Konradsson-Geuken Å, Holst S, Fisone G,
Ögren SO. Atypical but not typical antipsychotic drugs ameliorate phencyclidine-induced
emotional memory impairments in mice. Eur Neuropsychopharmacol. 2019 May;29(5):616-628.
Al Rawashdah S, Hamrouni A, Sadek B, Amer R, Metwaly M, Atatreh N, Ghattas MA. Molecular
modelling studies on ɑ7 nicotinic receptor 2 allosteric modulators yields novel filter-based
virtual screening protocol. J Mol Graph Model 2019; 92:44-54.
Alachkar A, Khan N, Łażewska D, Kieć-Kononowicz K, *Sadek B. Histamine H3 antagonist
E177 attenuates amnesia induced by dizocilpine without modulation of anxiety-like
behaviors in rats. Neuropsychiatr Dis Treat 2019;15:531-542.
Alsamri H, El Hasasna H, Al Dhaheri Y, Eid AH, Attoub S, Iratni R. Carnosol, a Natural
Polyphenol, Inhibits Migration, Metastasis, and Tumor Growth of Breast Cancer via
a ROS-Dependent Proteasome Degradation of STAT3. Front Oncol. 2019 Aug 8; 9:743. IF:
4,029
Al-Taee H, Azimullah S, Meeran MFN, Alaraj Almheiri MK, Al Jasmi RA, Tariq S, AB Khan
M, Adeghate E, Ojha S. β-caryophyllene, a dietary phytocannabinoids attenuates oxidative
stress, inflammation, apoptosis and prevents structural alterations of the myocardium
against doxorubicin-induced acute cardiotoxicity in rats: An in vitro and in vivo
study. Eur J Pharmacol. 2019 Sep 5;858:172467.
Aryappalli P, Shabbiri K, Masad RJ, Al-Marri RH, Haneefa SM, Mohamed YA, Arafat K,
Attoub S, Cabral-Marques O, Ramadi KB, Fernandez-Cabezudo MJ, Al-Ramadi BK. Inhibition
of Tyrosine-Phosphorylated STAT3 in Human Breast and Lung Cancer Cells by Manuka Honey
is Mediated by Selective Antagonism of the IL-6 Receptor. Int J Mol Sci. 2019 Sep
5; 20(18). IF: 4, 183
Bastaki SMA, Amir N, Więcek M, Kieć-Kononowicz K, *Sadek B. Influence of the novel
histamine H3 receptor antagonist/inverse agonist M39 on gastroprotection and PGE2
production induced by (R)-alpha-methylhistamine in C57BL/6 mice. Front. Pharmacol.
2019. In Press.
Behl S, Adem A, Hussain A, Singh J. Effects of rilpivirine, 17β-estradiol and β-naphthoflavone
on the inflammatory status of release of adipocytokines in 3T3-L1 adipocytes in vitro.
Mol Biol Rep. 2019 Jun;46(3):2643-2655.
Eissa N, Azimullah S, Jayaprakash P, Jayaraj RL, Reiner D, Ojha SK, Beiram R, Stark
H, Łażewska D, Kieć-Kononowicz K, *Sadek B. The dual-active histamine H3 receptor
antagonist and acetylcholine esterase inhibitor E100 ameliorates stereotyped repetitive
behavior and neuroinflammmation in sodium valproate induced autism in mice. Chem Biol
Interact 2019; 312:108775.
Elarabi H, Elrasheed A, Ali A, Shawky M, Hasan N, Gawad TA, Adem A, Marsden J.Suboxone
Treatment and Recovery Trial (STAR-T): Study Protocol for a Randomised Controlled
Trial of Opioid Medication Assisted Treatment with Adjunctive Medication Management
Using Therapeutic Drug Monitoring and Contingency Management. J Addict. 2019 Mar 5;2019:2491063.
Javed H, Azimullah S, Meeran MFN, Ansari SA, Ojha S. Neuroprotective Effects of Thymol,
a Dietary Monoterpene Against Dopaminergic Neurodegeneration in Rotenone-Induced Rat
Model of Parkinson's Disease. International Journal of Molecular Sciences 2019 Mar
27;20(7). pii: E1538. doi: 10.3390/ijms20071538. article
Khairnar SI, Mahajan UB, Patil KR, Patel HM, Shinde SD, Goyal SN, Belemkar S, Ojha
S, Patil CR. Disulfiram and its copper chelate attenuate cisplatin-induced acute nephrotoxicity
in rats via reduction of oxidative stress and inflammation. Biological and Trace Elements
Research 2019 Mar 1. doi: 10.1007/s12011-019-01683-w.
Lycopodium Attenuates Loss of Dopaminergic Neurons by Suppressing Oxidative Stress
and Neuroinflammation in a Rat Model of Parkinson's Disease. Jayaraj RL, Beiram R,
Azimullah S, Meeran MFN, Ojha SK, Adem A, Jalal FY. Molecules, 2019 Jun 10;24(11).
pii: E2182. doi: 10.3390
Meeran MFN, Al Taee H, Azimullah S, Tariq S, Adeghate E, Ojha S. β-Caryophyllene,
a natural bicyclic sesquiterpene attenuates doxorubicin-induced chronic cardiotoxicity
via activation of myocardial cannabinoid type-2 (CB(2) receptors in rats. Chemico
Biological Interactions 2019 May 1;304:158-167.
Nagoor MF, Shreesh Ojha. Protective effects of thymol against neurodegeneration in
a rat model of rotenone-induced Parkinson's disease. Cellular Physiology and Biochemistry,
2019, in the press. target α-synuclein aggregation in Parkinson's disease models.
Frontiers in Pharmacology 2019. doi: 10.3389/fphar.2018.01555.
Pantic J, Guilhaudis L, Musale V, Attoub S, Lukic ML, Mechkarska M, Conlon JM. Immunomodulatory,
insulinotropic, and cytotoxic activities of phylloseptins and plasticin-TR from the
Trinidanian leaf frog Phyllomedusa trinitatis. J Pept Sci. 2019, e3153. IF: 1.969
Patil AS, Singh AD, Mahajan UB, Patil CR, Ojha S, Goyal SN. Protective effect of omeprazole
and lansoprazole on β-receptor stimulated myocardial infarction in Wistar rats. Mol
Cell Biochem. 2019 Jun;456(1-2):105-113. doi:10.1007/s11010-019-03494-y.
Patil KR, Mahajan UB, Unger BS, Goyal SN, Belemkar S, Surana SJ, Ojha S, Patil CR.
Animal Models of Inflammation for screening of anti-inflammatory drugs: implications
for the discovery and development of phytopharmaceuticals. International Journal of
Molecular Sciences 2019 Sep 5;20(18). pii: E4367.
Salim M. A. Bastaki 1, Naheed Amir 1, Małgorzata Wiecek 2, Katarzyna Kiec´ -Kononowicz
2 and Bassem Sadek. Influence of the Novel Histamine H3 Receptor Antagonist/Inverse
Agonist M39 on Gastroprotection and PGE2 Production Induced by (R)-Alpha- Methylhistamine
in C57BL/6 Mice. Frontiers in Pharmaoclogy, 2019. (First and Co-corresponding author).
(2018)
Abdulrazzaq YM, Shafiullah M, Kochyil J, Padmanabhan R, Bastaki SMA. Ameliorative
effects of supplemental folinic acid on lamotrigine-induced fetal malformations in
the mouse. Mol Cell Biochem, 2018; doi: 10.1007/s11010-018-3285-0. (IF=2.56).
Al Ahmad M, Al Natour A, Attoub S, and H. Hassan A. Monitoring of the Budding Yeast
Cell Cycle Using Electrical Parameters. IEEE. 2018, IF: 3.244
Alachkar A, Latacz G, Siwek A, Lubelska A, Honkisz E, Gryboś A, Lazewska D, Handzlik
J, Stark H, Kiec-Kononowicz K, *Sadek B. Anticonvulsant evaluation of novel non-imidazole
histamine H3R antagonists in different convulsion models in rats. Pharmacol Biochem
Behav. 2018; 170:14-24.
Alachkar A, Łażewska D, Latacz G, Frank A, Siwek A, Lubelska A, Honkisz-Orzechowska
E, Handzlik J, Stark H, Kieć-Kononowicz K, *Sadek B. Studies on anticonvulsant effects
novel histamine H3R antagonists in electrically and chemically induced seizures in
rats. Int. J. Mol. Sci. 2018; 19(11), 3386.
Al-Ahmad MM, Amir N, Dhanasekaran S, John A, Abdulrazzaq YM, Ali BR, Bastaki SMA.
Genetic polymorphisms of cytochrome P450-1A2 (CYP1A2) among Emiratis. PLoSOne. 2017
Sep 21;12(9):e0183424. doi: 10.1371/journal.pone.0183424. eCollection2017. PubMed PMID: 28934216; PubMed Central PMCID: PMC5608188. (IF=2.80)
Ali MA, Damir HA, Amir N, Adeghate EA, Bastaki S, Murphy D, Adem A. Effects of long-term
dehydration on oxidative stress, apoptotic markers and neuropeptides in the gastric
mucosa of the dromedary camel Mol Cell Biochem 2018, Nov 26.
Arafat K, Al Kubaisy E, Sulaiman S, Karam S.M, Al Natour A, Hassan A.H, Attoub S.
SMARCAD1 in breast cancer progression. Cell Physiol Biochem J. 2018, 50(2):489-500.
IF: 5.104
Attoub S, Arafat K, Khalaf T, Sulaiman S, Iratni R. Frondoside A Enhances the Anti-Cancer
Effects of Oxaliplatin and 5-Fluorouracil on Colon Cancer Cells. Nutrients. 2018,
10:22-28. IF: 4.196
Bastaki SM, Abdulrazzaq YM, Shafiullah M, Więcek M, Kieć-Kononowicz K, *Sadek B. Anticonvulsant
and reproductive toxicological studies of the imidazole-based histamine H3R antagonist
2-18 in mice. Drug Des Devel Ther. 2018; 12:179-194.
Bastaki SMA Padol IT, Amir N, Hunt RH. Effect of aspirin and ibuprofen either alone
or in combination on gastric mucosa and bleeding time and on serum prostaglandin E2
and thromboxane A2 levels inn the anaesthetized rats in vivo. Mol Cell Biochem, 2018,
1-10. (IF=2.56)
Bastaki SMA, Adeghate E, Amir N, Ojha S, Oz M. Menthol inhibits Oxidative stress and
inflammation in acetic acid-induced colitis in rat colonic mucosa. Am J Trans Res,
2018, (IF=3.061). (First and Corresponding Author)
Eissa N, Al-Houqani M, Sadeq A, Ojha SK, Sasse A, *Sadek B. Current enlightenment
about etiology and Pharmacological Treatment of Autism Spectrum Disorder. Front Neurosci.
2018; 12:304.
Eissa N, Jayaprakash P, Azimullah S, Ojha SK, Al-Houqani M, Jalal FY, Łażewska D,
Kieć-Kononowicz K, *Sadek B. The histamine H3R antagonist DL77 attenuates autistic
behaviors in a prenatal valproic acid-induced mouse model of autism. Sci Rep. 2018;
8(1):13077.
Eissa N, Khan N, Ojha SK, Łażewska D, Kieć-Kononowicz K, *Sadek B. The histamine H3
receptor antagonist DL77 ameliorates MK801-induced memory deficits in rats. Front
Neurosci. 2018; 12:42.
Hammad FT, Ojha S, Azimullah S, Lubbad L. Does β-caryophyllene protect against renal
dysfunction following ischemia-reperfusion injury in the rat? Internation Journal
of Physiology, Pathophysiology and Pharmacology 2018 Dec 25;10(6):163-171.
Hu X, Rajesh M, Zhang J, Zhou S, Wang S, Sun J, Tan Y, Zheng Y, Cai L. Protection
by dimethyl fumarate against diabetic cardiomyopathy in type 1 diabetic mice likely
via activation of nuclear factor erythroid-2 related factor 2. Toxicol Lett. 2018
May 1;287:131-141. doi: 10.1016/j.toxlet.2018.01.020. Epub 2018 Feb 3.
Kalász H, Ojha S, Tekes K, Szőke É, Mohanraj R, Fahim M, Adeghate E, Adem A. Pharmacognostical
Sources of Popular Medicine To Treat Alzheimer's Disease. Open Med Chem J. 2018 Feb
16;12:23-35. doi: 10.2174/1874104501812010023. eCollection 2018.
Kalász H, Ojha S, Tekes K, Szőke É, Mohanraj R, Fahim M, Adeghate E, Adem A. Pharmacognostical
Sources of Popular Medicine to Treat Alzheimer's Disease Open Med Chem J. 2018 Feb
16;12:23-35.
Kurdi A, Hassan K, Venkataraman B, Rajesh M. Nootkatone confers hepatoprotective and
anti-fibrotic actions in a murine model of liver fibrosis by suppressing oxidative
stress, inflammation, and apoptosis. J Biochem Mol Toxicol. 2018 Feb;32(2). doi: 10.1002/jbt.22017. Epub 2017 Dec 7.
Mahajan UB, Patil PD, Chandrayan G, Patil CR, Agrawal YO, Shreesh Ojha, Goyal SN.
Eplerenone pretreatment protects the myocardium against ischaemia/reperfusion injury
through the phosphatidylinositol 3-kinase/Akt-dependent pathway in diabetic rats.
Molecular and Cellular Biochemistry 2018 Sep;446(1-2):91-103.
Meeran MFN, Laham F, Al-Taee H, Azimullah S, Shreesh Ojha. Protective effects of α-bisabolol
on altered hemodynamics, lipid peroxidation, and nonenzymatic antioxidants in isoproterenol-induced
myocardial infarction: in vivo and in vitro evidences. Journal of Biochemical and
Molecular Toxicology 2018 Aug 8: e22200.
Nagoor Meeran MF, Goyal SN, Suchal K, Sharma C, Patil CR, Shreesh Ojha. Pharmacological
properties, molecular mechanisms, and pharmaceutical development of asiatic acid:
a pentacyclic triterpenoid of therapeutic promise. Frontiers in Pharmacology 2018
Sep 4; 9:892.
Nagoor MF, Laham F, Azimullah S, Tariq S, Shreesh Ojha. α-Bisabolol abrogates isoproterenol-induced
myocardial infarction by inhibiting mitochondrial dysfunction and intrinsic pathway
of apoptosis in rats. Molecular and Cellular Biochemistry 2018 Aug 29.
SB Subramanya, B Venkataraman, MFN Meeran, SN Goyal, CR Patil, Shreesh Ojha. Therapeutic
potential of plants and plant derived phytochemicals against acetaminophen-induced
liver injury: evidence from preclinical studies. International Journal of Molecular
Sciences 2018 Nov 28;19(12). pii: E3776. doi: 10.3390/ijms19123776.
Shanmugam K, Ravindran S, Kurian GA, Rajesh M. Fisetin Confers Cardioprotection against
Myocardial Ischemia Reperfusion Injury by Suppressing Mitochondrial Oxidative Stress
and Mitochondrial Dysfunction and Inhibiting Glycogen Synthase Kinase 3β Activity.
Oxid Med Cell Longev. 2018 Feb 25;2018:9173436. doi: 10.1155/2018/9173436. eCollection 2018.
Shanmugam MK, Shen H, Tang FR, Arfuso F, Rajesh M, Wang L, Kumar AP, Bian J, Goh BC,
Bishayee A, Sethi G. Potential role of genipin in cancer therapy. Pharmacol Res. 2018
Jul;133:195-200. doi: 10.1016/j.phrs.2018.05.007. Epub 2018 May 24. Review.
SMA Bastaki, E Adeghate, N Amir, Shreesh Ojha, M Oz. Menthol inhibits oxidative stress
and inflammation in acetic acid-induced colitis in rat colonic mucosa. American Journal
of Translational Research 2018; 10(12): 4210–4222.
Sonawane VK, Mahajan UB, Shinde SD, Chatterjee S, Chaudhari SS, Bhangale HA, Shreesh
Ojha, Goyal SN, Kundu CN, Patil CR. A chemosensitizer drug: disulfiram prevents doxorubicin-induced
cardiac dysfunction and oxidative stress in rats. Cardiovascular Toxicology 2018 Oct;18(5):459-470.
Szczepans k, Karcz T, Mogilski, Siwek A, Kuder KJ, Latacz G, Kubacka M, Hagenow S,
Lubelska A, Olejarz A, Kotanska M, Sadek B, Stark H, Kiec-Kononowicz K. Synthesis
and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine
derivatives as histamine H3R ligands. Eur J Med Chem. 2018; 152:223-234.
UB Mahajan, G Chandrayan, CR Patil1, DS Arya, K Suchal, Y Agrawal, Shreesh Ojha, SN
Goyal. Eplerenone attenuates myocardial infarction in diabetic rats via modulation
of the PI3K-Akt pathway and phosphorylation of GSK-3β. American Journal of Translational
Research 2018;10(9).
V Raj, Shreesh Ojha, FC Howarth, PD Belur, SB Subramanya. Therapeutic potential of
benfotiamine and its molecular targets. European Review for Medical and Pharmacological
Sciences 22 (10), 3261-3273.
Vasaikar N, Mahajan U, Patil KR, Suchal K, Patil CR, Shreesh Ojha, Goyal SN. D-pinitol
attenuates cisplatin-induced nephrotoxicity in rats: impact on pro-inflammatory cytokines.
Chemico Biological Interactions 2018 Jun 25; 290: 6-11.
(2017)
Adem A, Madjid N, Kahl U, Holst S, Sadek B, Sandin J, Terenius L, Ögren SO. Nociceptin
and the NOP receptor in aversive learning in mice. Eur Neuropsychopharmacol.2017;
In Press.
Alachkar A, Łażewska D, Kieć-Kononowicz K, Sadek B. The histamine H3 receptor antagonist
E159 reverses memory deficits induced by dizocilpine in passive avoidance and novel
object recognition paradigm in rats. Front Pharmacol. 2017; 8:709.
Al-Ahmad MM, Amir N, Dhanasekaran S, John A, Abdulrazzaq YM, Ali BR, Bastaki SMA.
Genetic polymorphisms of cytochrome P450-1A2 (CYP1A2) among Emiratis. PLoSOne. 2017
Sep 21;12(9):e0183424. doi: 10.1371/journal.pone.0183424. eCollection2017. PubMed PMID: 28934216; PubMed Central PMCID: PMC5608188. (IF=2.80)
AlNeyadi SS, Adem A, Amer N, Salem AA, Abdou IM. Synthesis and in vitro biological
evaluation of new pyrimidines as glucagon-like peptide-1 receptor agonists. Bioorg
Med Chem Lett. 2017 Sep 14; 27: 5071-5075.
Aryappalli P, Al-Qubaisi SS, Attoub S, George JA, Arafat K, Ramadi KB, Mohamed YA,
Al-Dhaheri MM, Al-Sbiei A, Fernandez-Cabezudo MJ, Al-Ramadi BK. The IL-6/STAT3 Signaling
Pathway Is an Early Target of Manuka Honey-Induced Suppression of Human Breast Cancer
Cells. Front Oncol. 2017, 7:167.
Athamneh K, Hasasna HE, Samri HA, Attoub S, Arafat K, Benhalilou N, Rashedi AA, Dhaheri
YA, AbuQamar S, Eid A, Iratni R. Rhus coriaria increases protein ubiquitination, proteasomal
degradation and triggers non-canonical Beclin-1-independent autophagy and apoptotic
cell death in colon cancer cells. Sci Rep. 2017, 7(1):11633. IF: 4.259
Bastaki SM, Abdulrazzaq YM, Shafiullah M, Więcek M, Kieć-Kononowicz K, Sadek B. Anticonvulsant
and reproductive toxicological studies of the imidazole-based histamine H3R antagonist
2-18 in mice. Drug Des Devel Ther. 2017. Accepted.
Bastaki SMA, Padol IT, Ahmed F, Amir N, Hunt RH. Effect of aspirin and ibuprofen alone
or in combination on gastric mucosa, bleeding time, thromboxane A2, prostaglandin
E2 levels in the serum of anaesthetized rats in vivo. Moll Cell Biochem, 2017. DOI: 10.1007/s11010-017-3110-1 (IF=2.669).
Chaphalkar R, Apte KG, Talekar Y, Ojha SK, Nandave M. Antioxidants of Phyllanthus
emblica L. Bark Extract Provide Hepatoprotection against Ethanol-Induced Hepatic Damage:
A Comparison with Silymarin. Oxid Med Cell Longev. 2017;2017:3876040. doi: 10.1155/2017/3876040. PubMed PMID: 28168009.
Chaudhary G, Mahajan UB, Goyal SN, Ojha S, Patil CR, Subramanya SB. Protective effect
of Lagerstroemia speciosa against dextran sulfate sodium induced ulcerative colitis
in C57BL/6 mice. Am J Transl Res. 2017 Apr 15;9(4):1792-1800. eCollection 2017. PubMed
PMID: 28469784.
Conlon JM, Guilhaudis L, Leprince J, Coquet L, Mangoni ML, Attoub S, Jouenne T, King
JD. Peptidomic analysis of skin secretions of the Mexican burrowing toad Rhinophrynus
dorsalis (Rhinophrynidae): insight into the origin of host-defense peptides within
the Pipidae and characterization of a proline-arginine-rich peptide. Peptides. 2017,
Sep 23. IF: 2.778
Conlon JM, Musale V, Attoub S, Mangoni ML, Leprince J, Coquet L, Jouenne T, Abdel-Wahab
YHA, Flatt PR, Rinaldi AC. Cytotoxic peptides with insulin-releasing activities from
skin secretions of the Italian stream frog Rana italica (Ranidae). J Pept Sci. 2017,
23(10):769-776. IF: 1.972
Farahna M, Seke Etet PF, Osman SY, Yurt KK, Amir N, Vecchio L, Aydin I, Aldebasi YH,
Sheikh A, Chijuka JC, Kaplan S, Adem A. Garcinia kola aqueous suspension prevents
cerebellar neurodegeneration in long-term diabetic rat - a type 1 diabetes mellitus
model. J Ethnopharmacol. 2017 Jan 4;195:159-165.
Goyal SN, Prajapati CP, Gore PR, Patil CR, Mahajan UB, Sharma C, Talla SP, Ojha SK.
Therapeutic Potential and Pharmaceutical Development of Thymoquinone: A Multitargeted
Molecule of Natural Origin. Front Pharmacol. 2017 Sep 21;8:656. doi: 10.3389/fphar.2017.00656. PubMed PMID: 28983249;
Jahan S, Kumar D, Chaturvedi S, Rashid M, Wahajuddin M, Khan YA, Goyal SN, Patil CR,
Mohanraj R, Subramanya S, Ojha S. Therapeutic Targeting of NLRP3 Inflammasomes by
Natural Products and Pharmaceuticals: A Novel Mechanistic Approach for Inflammatory
Diseases. Curr Med Chem. 2017;24(16):1645-1670. doi: 10.2174/0929867324666170227121619. PubMed PMID: 28245768.
Kamble SM, Patel HM, Goyal SN, Noolvi MN, Mahajan UB, Ojha S, Patil CR. In silico
Evidence for Binding of Pentacyclic Triterpenoids to Keap1-Nrf2 Protein-Protein Binding
Site. Comb Chem High Throughput Screen. 2017;20(3):215-234. doi: 10.2174/1386207319666161214111822. PubMed PMID: 28024463.
Mahajan UB, Chandrayan G, Patil CR, Arya DS, Suchal K, Agrawal YO, Ojha S, Goyal SN.
The Protective Effect of Apigenin on Myocardial Injury in Diabetic Rats mediating
Activation of the PPAR-γ Pathway. Int J Mol Sci. 2017 Apr 4;18(4). pii: E756. doi: 10.3390/ijms18040756. PubMed PMID: 28375162.
Mahgoub E, Kumaraswamy SM, Kader KH, Venkataraman B, Ojha S, Adeghate E, Rajesh M.
Genipin attenuates cisplatin-induced nephrotoxicity by counteracting oxidative stress,
inflammation, and apoptosis. Biomed Pharmacother. 2017 Sep;93:1083-1097. doi: 10.1016/j.biopha.2017.07.018. Epub 2017 Jul 20. PubMed PMID: 28738532.
Mohammad M. Al-Ahmad, Naheed Amir, Subramanian Dhanasekaran, Anne John, Yousef M.
Abdulrazzaq, Bassam R. Ali & Salim M. A. Bastaki. Polymorphic N-acetyltransferase
(NAT2) Phenotyping and Genotyping among Emiratis. PLOS One, published September 21,
2017
Mukhopadhyay P, Horváth B, Rajesh M, Varga ZV, Gariani K, Ryu D, Cao Z, Holovac E,
Park O, Zhou Z, Xu MJ, Wang W, Godlewski G, Paloczi J, Nemeth BT, Persidsky Y, Liaudet
L, Haskó G, Bai P, Boulares AH, Auwerx J, Gao B, Pacher P. PARP inhibition protects
against alcoholic and non-alcoholic steatohepatitis. Journal of Hepatology. 2017;66(3):589-600
Nagoor Meeran MF, Javed H, Al Taee H, Azimullah S, Ojha SK. Pharmacological Properties
and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical
Development. Front Pharmacol. 2017 Jun 26;8:380. doi: 10.3389/fphar.2017.00380. eCollection 2017. PubMed PMID: 28694777.
Ojha S, Balaji V, Sadek B, Rajesh M. Beneficial effects of phytochemicals in diabetic
retinopathy: experimental and clinical evidence. European Review for Medicine and
Pharmacological Sciences. 2017; 21(11):2769-2783
Panda V, Mistry K, Sudhamani S, Nandave M, Ojha SK. Amelioration of Abnormalities
Associated with the Metabolic Syndrome by Spinacia oleracea (Spinach) Consumption
and Aerobic Exercise in Rats. Oxid Med Cell Longev. 2017;2017:2359389. doi: 10.1155/2017/2359389. PubMed PMID: 28798859
Patil PD, Mahajan UB, Patil KR, Chaudhari S, Patil CR, Agrawal YO, Ojha S, Goyal SN.
Past and current perspective on new therapeutic targets for Type-II diabetes. Drug
Des Devel Ther. 2017 May 22;11:1567-1583. doi: 10.2147/DDDT.S133453. eCollection 2017. PubMed PMID: 28579755.
Ramdhave AS, Ojha S, Nandave M. Energy intake correlates with the levels of fatty
acid synthase and insulin-like growth factor-1 in male and female C57BL/6 mice. Am
J Transl Res. 2017 Mar 15;9(3):830-844. eCollection 2017. PubMed PMID: 28386316.
Sadek B, Oz M, Nurulain SM, Jayaprakash P, Latacz G, Kieć-Kononowicz K, Szymańska
E. Phenylalanine derivatives with modulating effects on human α1-glycine receptors
and anticonvulsant activity in strychnine-induced seizure model in male adult rats.
Epilepsy Res. 2017, In Press.
Schübler M, Sadek B, Kottke T, Weizel L, Stark H. Synthesis, molecular properties
estimations, and dual dopamine D2 and D3 receptor activities of Benzothiazole-based
ligands. Front Chem. 2017; 5:64.
Suchal K, Malik S, Khan SI, Malhotra RK, Goyal SN, Bhatia J, Kumari S, Ojha S, Arya
DS. Protective effect of mangiferin on myocardial ischemia-reperfusion injury in streptozotocin-induced
diabetic rats: role of AGE-RAGE/MAPK pathways. Sci Rep. 2017 Feb 9;7:42027. doi: 10.1038/srep42027. PubMed PMID: 28181586.
Suchal K, Malik S, Khan SI, Malhotra RK, Goyal SN, Bhatia J, Ojha S, Arya DS. Molecular
Pathways Involved in the Amelioration of Myocardial Injury in Diabetic Rats by Kaempferol.
Int J Mol Sci. 2017 May 15;18(5). pii: E1001. doi: 10.3390/ijms18051001. PubMed PMID: 28505121.
Sultan A, Yang KHS, Isaev D, El Nebrisi E, Syed N, Khan N, Howarth CF, Sadek B, Oz
M. Thujone inhibits the function of α7-nicotinic acetylcholine receptors and impairs
nicotine-induced memory enhancement in one-trial passive avoidance paradigm. Toxicology
2017; 384:23-32.
(2016)
AbdulRazzaq YM, Padmanabhan R, Bastaki SA, Kochiyil J, Shafiullah M. (2016). Intrauterine
growth restriction and skeletal hyperplasia in Mouse Fetuses following maternal exposure
to aflatoxin B1 during early and late organogenesis. Hamdan Medical Journal, 2016.
Doi.org/10.7707/hmj.612.
Al Kubaisy E, Arafat K, De Wever O, Hassan A. H, Attoub S. (2016). SMARCAD1 knockdown
uncovers its role in breast cancer cell migration, invasion, and metastasis. Expert
Opin Ther Targets 2016, 13:1-9.
Al Shemaili J, Parekh KA, Newman RA, Hellman B, Woodward C, Adem A, Collin P, Adrian
TE. (2016). Pharmacokinetics in Mouse and Comparative Effects of Frondosides in Pancreatic
Cancer. Mar Drugs. 14(6). pii: E115. doi: 10.3390/md14060115.
Bastaki SMA, Al Ahmed MM, Zaabi A, Amir N, Adeghate E. (2016). Effect of turmeric
on colon histology, body weight, ulcer, IL-23, MPO and glutathione in acetic-acid-induced
inflammatory bowel disease in rats. BMC Comp Alt Med. 16:72 DOI: 10.1186/s12906-016-1057-5.
Chanchal SK, Mahajan UB, Siddharth S, Reddy N, Goyal SN, Patil PH, Bommanahalli BP,
Kundu CN, Patil CR, Ojha S. (2016). In vivo and in vitro protective effects of omeprazole
against neuropathic pain. Scientific Reports. 6:30007.
Dash M, Eid A, Subaiea G, Chang J, Deeb R, Masoud A, Renehan WE, Adem A, Zawia NH.
Developmental exposure to lead (Pb) alters the expression of the human tau gene and
its products in a transgenic animal model. Neurotoxicology. 2016 Jul;55:154-9.
El Hasasna H, Saleh A, Samri HA, Athamneh K, Attoub S, Arafat K, Benhalilou N, Alyan
S, Viallet J, Dhaheri YA, Eid A, Iratni R. (2016). Rhus coriaria suppresses angiogenesis,
metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and
nitric oxide pathways. Sci Rep 2016, 6:21144. doi: 10.1038/srep21144.
Ferdous Z, Qureshi MA, Jayaprakash P, Parekh K, John A, Oz M, Raza H, Dobrzynski H,
Adrian TE, Howarth FC. Different Profile of mRNA Expression in Sinoatrial Node from
Streptozotocin-Induced Diabetic Rat. (2016). PLoS One. 11(4):e0153934. doi: 10.1371.
Gore PR, Prajapati CP, Mahajan UB, Goyal SN, Belemkar S, Ojha S, Patil CR. (2016).
Protective Effect of Thymoquinone against Cyclophosphamide-Induced Hemorrhagic Cystitis
through Inhibiting DNA Damage and Upregulation of Nrf2 Expression. Int J Bioll Sci
12(8):944-53.
Goyal SN, Mahajan UB, Chandrayan G, Kumawat VS, Kamble S, Patil P, Agrawal YO, Patil
CR, Ojha S. (2016). Protective effect of oleanolic acid on oxidative injury and cellular
abnormalities in doxorubicin induced cardiac toxicity in rats. Am J Transl Res 8(1):60-9.
Hamadi N, Sheikh A, Madjid N, Lubbad L, Amir N, Shehab SA, Khelifi-Touhami F, Adem
A. Increased pro-inflammatory cytokines, glial activation and oxidative stress in
the hippocampus after short-term bilateral adrenalectomy. BMC Neurosci. 2016 Sep 1;17(1):61.
Javed H, Azimullah S, Abul Khair SB, Ojha S, Haque ME. (2016). Neuroprotective effect
of nerolidol against neuroinflammation and oxidative stress induced by rotenone. BMC
Neurosci 17(1):58.
Javed H, Azimullah S, Haque ME, Ojha SK. (2016). Cannabinoid Type 2 (CB2) Receptors
Activation Protects against Oxidative Stress and Neuroinflammation Associated Dopaminergic
Neurodegeneration in Rotenone Model of Parkinson's Disease. Front Neurosci 10:321.
Kurian GA, Rajagopal R, Vedantham S, Rajesh M. The Role of Oxidative Stress in Myocardial
Ischemia and Reperfusion Injury and Remodeling: Revisited. Oxid Med Cell Longev. 2016;2016:1656450.
Lozon Y, Sultan A, Lansdell SJ, Prytkova T, Sadek B, Yang KH, Howarth FC, Millar NS,
Oz M. (2016). Inhibition of human α7 nicotinic acetylcholine receptors by cyclic monoterpene
carveol. Eur J Pharmacol. 776:44-51.
Malik S, Suchal K, Bhatia J, Khan SI, Vasisth S, Tomar A, Goyal S, Kumar R, Arya DS,
Ojha SK. (2016). Therapeutic Potential and Molecular Mechanisms of Emblica officinalis
Gaertn in Countering Nephrotoxicity in Rats Induced by the Chemotherapeutic Agent
Cisplatin. Front Pharmacol 7:350.
Mukhopadhyay P, Horváth B, Rajesh M, Varga ZV, Gariani K, Ryu D, Cao Z, Holovac E,
Park O, Zhou Z, Xu MJ, Wang W, Godlewski G, Paloczi J, Nemeth BT, Persidsky Y, Liaudet
L, Haskó G, Bai P, Hamid Boulares A, Auwerx J, Gao B, Pacher P. (2016). PARP inhibition
protects against alcoholic and nonalcoholic steatohepatitis. J Hepatol. S0168-8278(16)30617-1.
doi: 10.1016/j.jhep.2016.10.023.
Nemmar A, Beegam S, Yuvaraju P, Yasin J, Tariq S, Attoub S, Ali BH. (2016). Ultra-small
superparamagnetic iron oxide nanoparticles acutely promote thrombosis and cardiac
oxidative stress and DNA damage in mice. Part Fibre Toxicol. 13(1):22.
Nurulain SM, Shafiullah M, Yasin J, Adem A, Kaabi JA, Tariq S, Adeghate E, Ojha S.
(2016). Terbufos-sulfone exacerbates cardiac lesions in diabetic rats: a sub-acute
toxicity study. Arh Hig Rada Toksikol. 67(2):126-35.
Ojha S, Al Taee H, Goyal S, Mahajan UB, Patil CR, Arya DS, Rajesh M. (2016). Cardioprotective
Potentials of Plant-Derived Small Molecules against Doxorubicin Associated Cardiotoxicity.
Oxid Med Cell Longev. 2016;2016:5724973.
Ojha S, Javed H, Azimullah S, Abul Khair SB, Haque ME. (2016). Glycyrrhizic acid Attenuates
Neuroinflammation and Oxidative Stress in Rotenone Model of Parkinson's Disease. Neurotoxicity
Research. 29(2):275-87.
Ojha S, Javed H, Azimullah S, Haque ME. (2016). β-Caryophyllene, a phytocannabinoid
attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic
neurons in a rat model of Parkinson disease. Mol Cell Biochem 418(1-2):59-70.
Ojha S, Kurdi A, Sadek B, Kaleem M, Cai L, Kamal MA, Rajesh M. (2016). Phytochemicals
as Prototypes for Pharmaceutical Leads Towards Drug Development Against Diabetic Cardiomyopathy.
Curr Pharm Des. 22(20):3058-70.
Ojha S, Venkataraman B, Kurdi A, Mahgoub E, Sadek B, Rajesh M. (2016). Plant-Derived
Agents for Counteracting Cisplatin-Induced Nephrotoxicity. Oxid Med Cell Longev. 2016;2016:4320374
Rajesh M, Cai L, Mukhopadhyay P, Vedantham S. (2016). Redox Signaling and Myocardial
Cell Death: Molecular Mechanisms and Drug Targets. Oxid Med Cell Longev. 2016;2016:3190753.
Sadek B, Khan N, Darras FH, Pockes S, Decker M. (2016). The dual-acting AChE inhibitor
and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine
in passive avoidance paradigm in rats. Physiol Behav 165:383-391
Sadek B, Saad A, Latacz G, Kuder K, Olejarz A, karcz T, Stark H, Kiec-Konowica K.
(2016). Nonimidazole-based h3R antagonists with anticonvulsant activity in different
seizure models in male adult rats. Drug Des Devel Ther. 10:3879-3898.
Sadek B, Saad A, Sadeq A, Jajal F, Stark H. (2016). Histamine H3 receptor as a potential
target for cognitive symptoms in neuropsychiatric diseases. Behav Brain Res. 312:415-430.
Sadek B, Saad A, Schwed JS, Weizel L,Walter M, Stark H. (2016). Anticonvulsant effects
of sisomeric nonimidazole histamine H3 receptor antagonists. Drug Des Devel Ther.
10:3633-3651.
Smail MM, Qureshi MA, Shmygol A, Oz M, Singh J, Sydorenko V, Arabi A, Howarth FC,
Al Kury L. (2016). Regional effects of streptozotocin-induced diabetes on shortening
and calcium transport in epicardial and endocardial myocytes from rat left ventricle.
Physiol Rep. 4(22). pii: e13034.
Suchal K, Bhatia J, Malik S, Malhotra RK, Gamad N, Goyal S, Nag TC, Arya DS, Ojha
S. (2016). Seabuckthorn Pulp Oil Protects against Myocardial Ischemia-Reperfusion
Injury in Rats through Activation of Akt/eNOS. Front Pharmacol 7:155.
Suchal K, Malik S, Gamad N, Malhotra RK, Goyal SN, Chaudhary U, Bhatia J, Ojha S,
Arya DS. (2016). Kaempferol Attenuates Myocardial Ischemic Injury via Inhibition of
MAPK Signaling Pathway in Experimental Model of Myocardial Ischemia-Reperfusion Injury.
Oxid Med Cell Longev. 2016:7580731.
Suchal K, Malik S, Gamad N, Malhotra RK, Goyal SN, Ojha S, Kumari S, Bhatia J, Arya
DS. (2016). Mangiferin protect myocardial insults through modulation of MAPK/TGF-β
pathways. Eur J Pharmacol. 776:34-43.
(2015)
Agil A, Elmahallawy EK, Rodríguez-Ferrer JM, Adem A, Bastaki SM, Al-Abbadi I, Fino
Solano YA, Navarro-Alarcón M. (2015). Melatonin increases intracellular calcium in
the liver, muscle, white adipose tissues and pancreas of diabetic obese rats. Food
Funct, 6(8):2671-8. doi: 10.1039/ c5fo00590f.
Ahmed W, Philip PS, Attoub S, Khan G. (2015). Epstein-Barr virus-infected cells release
Fas ligand in exosomal fractions and induce apoptosis in recipient cells via the extrinsic
pathway. J Gen Virol, 96(12):3646-59. doi:10.1099/ jgv.0.000313. PubMed PMID: 26467838.
Ali RM, Al Kury LT, Yang KH, Qureshi A, Rajesh M, Galadari S, Shuba YM, Howarth FC,
Oz M. (2015). Effects of cannabidiol on contractions and calcium signaling in rat
ventricular myocytes. Cell Calcium, 57(4):290-9. doi:10.1016/j. ceca.2015.02.001. PubMed PMID: 25711828.
Alketbi A, Attoub S. (2015). Notch Signaling in Cancer: Rationale and Strategies for
Targeting. Curr Cancer Drug Targets, 15(5):364-74. PubMed PMID: 26239151.
Al-Tabakha MM, Arida AI, Fahelelbom KM, Sadek B, Saeed DA, Abu Jarad RA, Jawadi J.
(2015). Influence of capsule shell composition on the performance indicators of hypromellose
capsule in comparison to hard gelatin capsules. Drug Dev Ind Pharm, 41(10):1726-37.
doi:10.3109/03639045.2014.1002409. PubMed PMID: 25586554.
Al-Tabakha MM, Arida AI, Fahelelbom KMS, Sadek B, Abu Jarad RA. (2015). Performances
of new generation of delayed release Capsules. J Young Pharm, 7:36-44.
Attoub S, Arafat K, Hammadi NK, Mester J, Gaben AM. (2015). Akt2 knock-down reveals
its contribution to human lung cancer cell proliferation, growth, motility, invasion
and endothelial cell tube formation. Sci Rep, 5:12759. doi:10.1038/srep12759. PubMed PMID: 26234648.
Bastaki SMA. (2015). Pharmacotherapy of nonnutritive sweeteners in diabetes mellitus.
Int J Diabetes & Metab, 23:11-22.
Chandranath IR, Bastaki SMA, AlMajid, MA, Singh J. (2014). Protective mechanisms of
the gastrointestinal mucosa: a review. Research Trends: Curr Top in Pharmacol, 18:1-28.
Dinc S, Caydere M, Akgul G, Yenidogan E, Hücümenoglu S, Rajesh M. (2015). Methylene
Blue inhibits the inflammatory process of the acetic acid-induced colitis in the rat
colonic mucosa. Int Surg, June 10 [Epub ahead of print] PubMed PMID: 26062761.
Goyal SN, Sharma C, Mahajan UB, Patil CR, Agrawal YO, Kumari S, Arya DS, Ojha S. (2015).
Protective effects of cardamom in isoproterenol-induced myocardial infarction in rats.
Int J Mol Sci, 16(11):27457- 69. doi: 10.3390/ijms161126040. PubMed PMID: 26593900.
Hamouda NN, Sydorenko V, Qureshi MA, Alkaabi JM, Oz M, Howarth FC. (2015). Dapagliflozin
reduces the amplitude of shortening and Ca(2+) transient in ventricular myocytes from
streptozotocin-induced diabetic rats. Mol Cell Biochem, 400(1-2):57-68. doi: 10.1007/s11010-014-2262-5. Epub 2014 Oct 29. PubMed PMID: 25351341.
Islam B, Sharma C, Adem A, Aburawi E, Ojha S. (2015). Insight into the mechanism of
polyphenols on the activity of HMGR by molecular docking. Drug Des Devel Ther, 9:4943-51.
doi: 10.2147/ DDDT.S86705. eCollection 2015. PubMed PMID: 26357462.
Jalal FY, Yang Y, Thompson JF, Roitbak T, Rosenberg GA. (2015). Hypoxia-induced neuroinflammatory
white-matter injury reduced by minocycline in SHR/SP. J Cereb Blood Flow Metab, 35(7):1145-
53. doi: 10.1038/jcbfm.2015.21. PubMed PMID: 25712499.
Khan G, Ahmed W, Philip PS, Ali MH, Adem A. (2015). Healthy rabbits are susceptible
to EpsteinBarr virus infection and infected cells proliferate in immunosuppressed
animals. Virol J, 12:28. doi: 10.1186/s12985-015-0260-1. PubMed PMID: 25851649.
Khan N, Farooq AD, Sadek B. (2015). Investigation of cyclooxygenase and signaling
pathways involved in human platelet aggregation mediated by synergistic interaction
of various agonists. Drug Des Devel Ther, 9:3497- 506. doi:10.2147/DDDT.S84335. eCollection 2015. PubMed PMID: 26185418.
Manzo G, Scorciapino MA, Srinivasan D, Attoub S, Mangoni ML, Rinaldi AC, Casu M, Flatt
PR, Conlon JM. (2015). Conformational analysis of the host-defense peptides pseudhymenochirin-1Pb
and -2Pa and design of analogues with insulin-releasing activities and reduced toxicities.
J Nat Prod, 78(12):3041-8. doi:10.1021/acs. jnatprod.5b00843. PubMed PMID: 26606380.
Nurulain S, Prytkova T, Sultan AM, Ievglevskyi O, Lorke D, Yang KH, Petroianu G, Howarth
FC, Kabbani N, Oz M. (2015). Inhibitory actions of bisabolol on α7-nicotinic acetylcholine
receptors. Neuroscience, 306:91-9. doi:10.1016/j.neuroscience.2015.08.019. PubMed PMID: 26283025.
Nurulain SM, Ojha S, Shafiullah M, Khan N, Oz M, Sadek B. (2015). Protective effects
of the antihistamine promethazine against acute paraxon-methyl and dicrotophos toxicity
in adult rats. Int J Clin Exp Med, 8(10):17891-901. eCollection 2015. PubMed PMID:
26770383.
Nurulain SM, Ojha S, Tekes K, Shafiullah M, Kalasz H, Adem A. (2015). Efficacy of
N-acetylcysteine, glutathione, and ascorbic acid in acute toxicity of paraoxon to
Wistar rats: survival study. Oxid Med Cell Longev, 2015:329306. doi:10.1155/2015/329306. PubMed PMID: 26167240.
Ojha S, Azimullah S, Mohanraj R, Sharma C, Yasin J, Arya DS, Adem A. (2015). Thymoquinone
Protects against Myocardial Ischemic Injury by Mitigating Oxidative Stress and Inflammation.
Evid Based Complement Alternat Med, 2015:143629. doi: 10.1155/2015/143629. PubMed PMID: 26101531.
Ojha S, Javed H, Azimullah S, Abul Khair SB, Haque ME. (2015). Neuroprotective potential
of ferulic acid in the rotenone model of Parkinson's disease. Drug Des Devel Ther,
Oct 7; 9:5499-510. doi: 10.2147/DDDT.S90616. eCollection 2015. PubMed PMID: 26504373; PubMed Central PMCID: PMC4603721.
Ojha SK, Sharma C, Golechha MJ, Bhatia J, Kumari S, Arya DS. (2015). Licorice treatment
prevents oxidative stress, restores cardiac function, and salvages myocardium in rat
model of myocardial injury. Toxicol Ind Health, 31(2):140-52. doi: 10.1177/0748233713491800. PubMed PMID: 23771872.
Onopchenko OV, Kosiakova GV, Oz M, Klimashevsky VM, Gula NM. (2015). N-stearoylethanolamine
restores pancreas lipid composition in obesity-induced insulin resistant rats. Lipids,
50(1):13-21. doi: 10.1007/s11745-014-3960-1. Epub 2014 Oct 15. PubMed PMID: 25314940.
Oz M, Lozon Y, Sultan A, Yang KH, Galadari S. (2015). Effects of monoterpenes on ion
channels of excitable cells. Pharmacol Ther, 152:83-97. doi:10.1016/j. pharmthera.2015.05.006. PubMed PMID: 25956464.
Patil KR, Mohapatra P, Patel HM, Goyal SN, Ojha S, Kundu CN, Patil CR. (2015). Pentacyclic
triterpenoids inhibit IKKβ mediated activation of NF-κB pathway: in silico and in
vitro evidences. PLoS One, 10(5):e0125709. doi:10.1371/ journal.pone.0125709. eCollection 2015. PubMed PMID: 25938234.
Sadek B, Khanian SS, Ashoor A, Prytkova T, Ghattas MA, Atatreh N, Nurulain SM, Yang
KH, Howarth FC, Oz M. (2015). Effects of antihistamines on the function of human α7-nicotinic
acetylcholine receptors. Eur J Pharmacol, 746:308-16. doi: 10.1016/j.ejphar.2014.10.046. PubMed PMID: 25445036.
Sharma C, Sadek B, Goyal SN, Sinha S, Kamal MA, Ojha S. (2015). Small Molecules from
Nature Targeting G-Protein Coupled Cannabinoid Receptors: Potential Leads for Drug
Discovery and Development. Evid Based Complement Alternat Med, 2015:238482. doi: 10.1155/2015/238482. PubMed PMID: 26664449.
Zadjali SA, Nemmar A, Fahim MA, Azimullah S, Subramanian D, Yasin J, Amir N, Hasan
MY, Adem A. (2015). Lead exposure causes thyroid abnormalities in diabetic rats. (2015).
Int J Clin Exp Med. 8(5):7160-7. eCollection 2015. PubMed PMID: 26221254.
Bastaki SMA, Zaabi A, Amir N, Adeghate E. (2015). Effect of turmeric on serum and
colonic mucosa levels of glutathione, myeloperoxidase3, and IL-23 in acetic acid-induced
inflammatory bowel disease in rats. J Gastroenterol Hepatol, 30 (suppl, 4) 28-159.
