Molecular Basis of Human Diseases (GENT601)

The course addresses five fundamental mechanisms of human diseases and how to explore them in the laboratory. It provides in-depth analysis of cellular detoxification, cellular bioenergetics, mitochondrial disturbances, malignant transformation and inflammation. The topics are covered in ten seminars. Students need to write a full report on each topic, which composes 50% of the grade. The other aspect of the course includes five laboratory sessions that cover cellular thiols, cellular bioenergetics, intracellular caspases and in vitro assessment of cytotoxicities.

Credit Hours : 2

Bioinformatics and Genomics (GENT602)

Bioinformatics applies the principles of information science and technology to answer some of today's most complex questions in the life sciences. Its research lies in the development and application of computational approaches for the storage, analysis and interpretation of biological data. In the medical arena, particularly in functional genomics, researchers are currently using technologies that yield vast amounts of complex data. This data first needs to be stored in integrated, highly curated and user friendly databases. Analytical algorithms and analysis pipelines need to be applied to the data in order to extract as much information from the experiment as possible. Finally, in order for the life science community to be able to use these algorithms, they must be packaged in user-friendly, easily accessible tools. Bioinformatics thus has three components: database structure, data mining and data analysis procedures, and software development.

Credit Hours : 2

Mechanisms of Malignancies and Hematology (HONC320)

This course covers an overview of hematology and oncology at the level of the third year medical student. The course consists of basic/clinical science lectures combined with relevant laboratory teaching and problem based learning (PBL) in relation with hematologic and oncologic disorders. Students will study basic mechanisms of cancer development, progression, diagnosis, therapy, screening and prevention. They will also study fundamental concepts of hematology including blood-forming organs and the origin and function of blood cells and plasma. They will also examine the theoretical and clinical aspects of normal and pathological conditions of erythrocytes, leukocytes, platelets, coagulation and blood group systems.

Credit Hours : 7

Course Learning Outcomes

1. Demonstrate Capability To Communicate Professionally And Learn In Collaborative Groups.
2. Demonstrate Life-Long Learning Skills For Personal And Professional Growth And Development.
3. Describe The Basic Mechanisms Of Cancer Development And Progression.
4. Describe The Pathology Of Anaemia.
5. Discuss The Pathogenesis, Diagnosis And Treatment Of Hematopoietic Disorders.
6. Explain Hemostatic And Coagulation Disorders.

Pathology (PATH224)

This course covers the general mechanisms underlying the alteration of the normal structures and functions of tissues when there is disease and the body’s response. Students will appreciate the mechanisms by which the body restores normal structure and function following a disease process. It will also introduce students to basic concepts in neoplasia.

Credit Hours : 3

Course Learning Outcomes

1. Compare And Contrast Between Edema And Congestion.
2. Compare And Contrast The Tissue Manifestations Of Different Infectious Agents (Bacteria, Viruses, Parasites, Atypical Bacteria And Fungi).
3. Define Grading And Explain Its Significance In Patient Management.
4. Define Inflammation, List Etiological Factors And Describe Gross And Microscopic Findings In Acute And Chronic Inflammation.
5. Define Neoplasia, List Etiological Factors And Compare And Contrast Between Benign And Malignant Neoplasms.
6. Demonstrate Ability To Search For Updated Medical Information Through Various Reliable Medical Resources.
7. Describe Effects Of Exposure To Chemical And Physical Environmental Insults On Human Body (Heavy Metals, Smoking, Radiation).
8. Describe Pathogenesis Of Thrombosis And Emboli And List Consequences Of Thrombosis And Embolism.
9. Describe The Healing Process And Repair Occurring After Tissue Injury And List Examples Of Abnormal Forms Of Healing.
10. Discuss The Causes And Consequences Of Hemorrhage And Shock On The Body.
11. Explain The Mechanisms Of Cellular Adaptation, Reversible And Irreversible Cell Injury.
12. List Causes Of Intracellular Pigment Deposition And Types Of Pathological Calcifications And Amyloidosis.
13. List Common Congenital Conditions And Explain Their Causes And Pathogenesis (E.G. Malformations, Disruption, Sequence, Deformation, Syndrome, Agenesis, Aplasia, Atresia, Hypoplasia, Hyperplasia, Hypotrophy, Hypertrophy, Dysplasia).
14. List Examples Of Tumor Markers.
15. Practice Effective Communication Skills Through Pathology Lab Sessions & Student Presentation.

Human Genetics (PATH602)

Genetic disorders are a major cause of morbidity and mortality in UAE as well as other populations. Understanding the molecular and cellular basis of these disorders is crucial for the development of effective prevention, diagnosis and treatment. This course will cover the basics and the advanced aspects human genetics.

Credit Hours : 2

Course Learning Outcomes

1. Carry Out Critical Evaluation And Efficient Presentation Of Published Articles And Scientific Writing In Genetics.
2. Describe The Principles And Modes Of Inheritance And Their Exceptions.
3. Describe The Principles Of Population Genetics And Hardy-Weinberg Principles.
4. Recognize The Various Approaches Used In The Diagnosis, Prevention And Gene Therapy Of Genetic Conditions.
5. Recognize The Various Types Of Genetic Aberrations With Their Biological Implications.

Renal and Urogenital Systems (WMEX350)

This course covers the essentials of history taking and physical examination pertaining to renal and urology systems. The course is designed to cover common topics and conditions in the field of nephrology, nephropathology and urology. It commences from basic medical sciences reviewing renal and urology systems embryological development, structure and function. The course highlights aberrant development, structure and function. The course is constructed of theme based weeks. Hence, lectures, practicals and problem based learning revolve around a specific theme and its differential diagnoses. Interactive learning is the core teaching method with one-to-one feedback by experienced clinicians and tutors. A structured checklist is used the faculty tutors to measure student performance and provide constructive feedback. Self-reflection and peer feedback are also encouraged. Standardized (simulated) patients of community volunteers provide an opportunity to practice and master physical examination in an optimal environment. The course dedicates time to cover medico-legal aspects in the practice of medicine supplemented by field trip to Dubai Police Headquarters. The course is comprehensive, yet challenging and stimulates students to employ medial reasoning, and clinical knowledge in solving patients related conditions.

Credit Hours : 6

Course Learning Outcomes

1. Demonstrate Capability To Communicate Professionally And Learn In Collaborative Groups.
2. Demonstrate Life-Long Learning Skills For Personal And Professional Growth And Development.
3. Describe The Basic Mechanisms Of Development And Progression Of Disorders Of Genital Organs.
4. Describe The Pathophysiology Of Acute Injury Of Kidney.
5. Discuss The Pathogenesis, Diagnosis And Treatment Of Chronic Disorders Of Kidney.
6. Outline Mechanisms Of Glomerulonephritis.